Dried Blood Spot Analysis for Therapeutic Drug Monitoring of Linezolid in Patients with Multidrug-Resistant Tuberculosis

Linezolid is a promising antimicrobial agent for the treatment of multidrug-resistant tuberculosis (MDR-TB), but its use is limited by toxicity. Therapeutic drug monitoring (TDM) may help to minimize toxicity while adequate drug exposure is maintained. Conventional plasma sampling and monitoring mig...

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Hlavní autoři: Vu, D. H., Bolhuis, M. S., Koster, R. A., Greijdanus, B., de Lange, W. C. M., van Altena, R., Brouwers, J. R. B. J., Uges, D. R. A., Alffenaar, J. W. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Analytical Procedures
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486591/
https://ncbi.nlm.nih.gov/pubmed/22926568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01054-12
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