T-2307 Causes Collapse of Mitochondrial Membrane Potential in Yeast

T-2307, an arylamidine compound, has been previously reported to have broad-spectrum in vitro and in vivo antifungal activities against clinically significant pathogens, including Candida species, Cryptococcus neoformans, and Aspergillus species, and is now undergoing clinical trials. Here we invest...

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Главные авторы: Shibata, Tatsuya, Takahashi, Toshinari, Yamada, Eio, Kimura, Akiko, Nishikawa, Hiroshi, Hayakawa, Hiroyoshi, Nomura, Nobuhiko, Mitsuyama, Junichi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Mechanisms of Action: Physiological Effects
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486560/
https://ncbi.nlm.nih.gov/pubmed/22948882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05954-11
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