Organic Radical Contrast Agents for Magnetic Resonance Imaging

We report a molecular design that provides an intravenously injectable organic radical contrast agent (ORCA) that has molecular r(1) ≈ 5 mM(−1)s(−1). The ORCA is based on spirocyclohexyl nitroxide radicals and polyethylene glycol chains conjugated to a generation 4 polypropylenimine dendrimers scaff...

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Autori principali: Rajca, Andrzej, Wang, Ying, Boska, Michael, Paletta, Joseph T., Olankitwanit, Arnon, Swanson, Michael A., Mitchell, Deborah G., Eaton, Sandra S., Eaton, Gareth R., Rajca, Suchada
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486519/
https://ncbi.nlm.nih.gov/pubmed/22974177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3079829
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