Conserved Fiber-Penton Base Interaction Revealed by Nearly Atomic Resolution Cryo-Electron Microscopy of the Structure of Adenovirus Provides Insight into Receptor Interaction

Adenovirus (Ad) cell attachment is initiated by the attachment of the fiber protein to a primary receptor (usually CAR or CD46). This event is followed by the engagement of the penton base protein with a secondary receptor (integrin) via its loop region, which contains an Arg-Gly-Asp (RGD) motif, to...

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Detalhes bibliográficos
Main Authors: Cao, Changchun, Dong, Xiaoyan, Wu, Xiaobing, Wen, Boyun, Ji, Gang, Cheng, Lingpeng, Liu, Hongrong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486510/
https://ncbi.nlm.nih.gov/pubmed/22951835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01608-12
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