Probing the Early Temporal and Spatial Interaction of the Sindbis Virus Capsid and E2 Proteins with Reverse Genetics

A 7-Å cryoelectron microscopy-based reconstruction of Sindbis virus (SINV) was recently generated. Fitting the crystal structure of the SINV capsid protein (Cp) into the density map revealed that the F2-G2 loop of the Cp was shifted away from cytoplasmic domain of E2 (cdE2) in the 7-Å reconstruction...

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Bibliographic Details
Main Authors: Snyder, Jonathan E., Berrios, Christian J., Edwards, Thomas J., Jose, Joyce, Perera, Rushika, Kuhn, Richard J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486501/
https://ncbi.nlm.nih.gov/pubmed/22951842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01220-12
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