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A Heterologous Coiled Coil Can Substitute for Helix I of the Sindbis Virus Capsid Protein

Alphavirus core assembly proceeds along an assembly pathway involving a dimeric assembly intermediate. Several regions of the alphavirus capsid protein have been implicated in promoting and stabilizing this dimerization, including a putative heptad repeat sequence named helix I. This sequence, which...

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Detalhes bibliográficos
Main Authors: Perera, Rushika, Navaratnarajah, Chanakha, Kuhn, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165231/
https://ncbi.nlm.nih.gov/pubmed/12857904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8345-8353.2003
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