A Conserved UDP-Glucose Dehydrogenase Encoded outside the hasABC Operon Contributes to Capsule Biogenesis in Group A Streptococcus

Group A Streptococcus (GAS) is a human-specific bacterial pathogen responsible for serious morbidity and mortality worldwide. The hyaluronic acid (HA) capsule of GAS is a major virulence factor, contributing to bloodstream survival through resistance to neutrophil and antimicrobial peptide killing a...

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Detalhes bibliográficos
Main Authors: Cole, Jason N., Aziz, Ramy K., Kuipers, Kirsten, Timmer, Anjuli M., Nizet, Victor, van Sorge, Nina M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486382/
https://ncbi.nlm.nih.gov/pubmed/22961854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01317-12
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