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Propagation of conformational changes in Ni(II)-substituted aspartate transcarbamoylase: Effect of active-site ligands on the regulatory chains

Although the importance of ligand-promoted conformational changes in allosteric enzymes has been recognized, it often has been difficult to determine whether the effects of binding are propagated to remote positions in different chains. Efforts were made, therefore, to demonstrate that changes due t...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Johnson, Ronald S., Schachman, H. K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1980
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348637/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6990418/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.1995
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