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Propagation of conformational changes in Ni(II)-substituted aspartate transcarbamoylase: Effect of active-site ligands on the regulatory chains

Although the importance of ligand-promoted conformational changes in allosteric enzymes has been recognized, it often has been difficult to determine whether the effects of binding are propagated to remote positions in different chains. Efforts were made, therefore, to demonstrate that changes due t...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Johnson, Ronald S., Schachman, H. K.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1980
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348637/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6990418/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.1995
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