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Propagation of conformational changes in Ni(II)-substituted aspartate transcarbamoylase: Effect of active-site ligands on the regulatory chains

Although the importance of ligand-promoted conformational changes in allosteric enzymes has been recognized, it often has been difficult to determine whether the effects of binding are propagated to remote positions in different chains. Efforts were made, therefore, to demonstrate that changes due t...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Proc Natl Acad Sci U S A
Κύριοι συγγραφείς: Johnson, Ronald S., Schachman, H. K.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 1980
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348637/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6990418/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.1995
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