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Effect of introduction of small alkyl groups on mRNA function.
Treatment of RNA with dimethyl sulfate methylates only nitrogens, preferentially the 7 position of guanosine, whereas treatment with ethylnitrosourea ethylates mainly oxygens, preferentially the phosphodiester groups. Two plant viral mRNAs were modified with these two reagents at levels of 4-28 alky...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1980
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6929532/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.1983 |
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