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HIV-1 Replication and APOBEC3 Antiviral Activity Are Not Regulated by P Bodies

The APOBEC3 cytidine deaminases play a critical role in host-mediated defense against exogenous viruses, most notably, human immunodeficiency virus type-1 (HIV-1) and endogenous transposable elements. APOBEC3G and APOBEC3F interact with numerous proteins that regulate cellular RNA metabolism, includ...

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Main Authors: Phalora, Prabhjeet K., Sherer, Nathan M., Wolinsky, Steven M., Swanson, Chad M., Malim, Michael H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486339/
https://ncbi.nlm.nih.gov/pubmed/22915799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00595-12
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