Reconstitution of the Entire Hepatitis C Virus Life Cycle in Nonhepatic Cells

Hepatitis C virus (HCV) is a human hepatotropic virus, but the relevant host factors restricting HCV infection to hepatocytes are only partially understood. We demonstrate that exogenous expression of defined host factors reconstituted the entire HCV life cycle in human nonhepatic 293T cells. This s...

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Bibliografische gegevens
Hoofdauteurs: Da Costa, Daniel, Turek, Marine, Felmlee, Daniel J., Girardi, Erika, Pfeffer, Sébastien, Long, Gang, Bartenschlager, Ralf, Zeisel, Mirjam B., Baumert, Thomas F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Virus-Cell Interactions
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486316/
https://ncbi.nlm.nih.gov/pubmed/22896615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01066-12
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