Reconstitution of the Entire Hepatitis C Virus Life Cycle in Nonhepatic Cells

Hepatitis C virus (HCV) is a human hepatotropic virus, but the relevant host factors restricting HCV infection to hepatocytes are only partially understood. We demonstrate that exogenous expression of defined host factors reconstituted the entire HCV life cycle in human nonhepatic 293T cells. This s...

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Detalhes bibliográficos
Main Authors: Da Costa, Daniel, Turek, Marine, Felmlee, Daniel J., Girardi, Erika, Pfeffer, Sébastien, Long, Gang, Bartenschlager, Ralf, Zeisel, Mirjam B., Baumert, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486316/
https://ncbi.nlm.nih.gov/pubmed/22896615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01066-12
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