A Virus-Like Particle That Elicits Cross-Reactive Antibodies to the Conserved Stem of Influenza Virus Hemagglutinin

The discovery of broadly neutralizing antibodies that recognize highly conserved epitopes in the membrane-proximal region of influenza virus hemagglutinin (HA) has revitalized efforts to develop a universal influenza virus vaccine. This effort will likely require novel immunogens that contain these...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schneemann, Anette, Speir, Jeffrey A., Tan, Gene S., Khayat, Reza, Ekiert, Damian C., Matsuoka, Yumiko, Wilson, Ian A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486276/
https://ncbi.nlm.nih.gov/pubmed/22896619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01694-12
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