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Limited DNase I nicking as a probe of gene conformation.

We have extended the use of pancreatic DNase I as a probe of chromatin structure by exploring the accessibility of an active gene to the introduction of the first single-stranded nick. We show by a target analysis that the beta-globin gene is about 25-fold more sensitive to single-site nicking than...

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Bibliografische gegevens
Hoofdauteurs: Zasloff, M, Camerini-Otero, R D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1980
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC348618/
https://ncbi.nlm.nih.gov/pubmed/6929527
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