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HtrA1 Is a Novel Antagonist Controlling Fibroblast Growth Factor (FGF) Signaling via Cleavage of FGF8

Accumulating evidence suggests that HtrA1 (high-temperature requirement A1) is involved in modulating crucial cellular processes and implicated in life-threatening diseases, such as cancer and neuropathological disorders; however, the exact functions of this protease in vivo remain unknown. Here, we...

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Detalhes bibliográficos
Main Authors: Kim, Goo-Young, Kim, Ho-Young, Kim, Hyun-Taek, Moon, Jeong-Mi, Kim, Cheol-Hee, Kang, Seongman, Rhim, Hyangshuk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486155/
https://ncbi.nlm.nih.gov/pubmed/22949504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00872-12
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