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Poly(A) Binding Protein C1 Is Essential for Efficient L1 Retrotransposition and Affects L1 RNP Formation

Poly(A) binding proteins (PABPs) specifically bind the polyadenosine tail of mRNA and have been shown to be important for RNA polyadenylation, translation initiation, and mRNA stability. Using a modified L1 retrotransposition vector, we examined the effects of two PABPs (encoded by PABPN1 and PABPC1...

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Detalles Bibliográficos
Autores principales: Dai, Lixin, Taylor, Martin S., O'Donnell, Kathryn A., Boeke, Jef D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486150/
https://ncbi.nlm.nih.gov/pubmed/22907758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06785-11
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