Ablation of ALCAT1 Mitigates Hypertrophic Cardiomyopathy through Effects on Oxidative Stress and Mitophagy

Oxidative stress causes mitochondrial dysfunction and heart failure through unknown mechanisms. Cardiolipin (CL), a mitochondrial membrane phospholipid required for oxidative phosphorylation, plays a pivotal role in cardiac function. The onset of age-related heart diseases is characterized by aberra...

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Main Authors: Liu, Xiaolei, Ye, Benlan, Miller, Shane, Yuan, Huijuan, Zhang, Hongxiu, Tian, Liang, Nie, Jia, Imae, Rieko, Arai, Hiroyuki, Li, Yuanjian, Cheng, Zeneng, Shi, Yuguang
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2012
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486149/
https://ncbi.nlm.nih.gov/pubmed/22949503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01092-12
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