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Insulin-Like Growth Factor 1 Mediates Negative Feedback to Somatotroph GH Expression via POU1F1/CREB Binding Protein Interactions

Circulating insulin-like growth factor 1 (IGF-1) has been shown to act as a negative feedback regulator of growth hormone (GH) gene expression; however, the mechanism of this negative feedback is poorly understood. Activation and regulation of GH gene expression require the binding of the transcript...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Romero, Christopher J., Pine-Twaddell, Elyse, Sima, Daniela I., Miller, Ryan S., He, Ling, Wondisford, Fredric, Radovick, Sally
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486141/
https://ncbi.nlm.nih.gov/pubmed/22890843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00171-12
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