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The Meningococcal Adhesin NhhA Provokes Proinflammatory Responses in Macrophages via Toll-Like Receptor 4-Dependent and -Independent Pathways

Activation of macrophages by Toll-like receptors (TLRs) and functionally related proteins is essential for host defense and innate immunity. TLRs recognize a wide variety of pathogen-associated molecules. Here, we demonstrate that the meningococcal outer membrane protein NhhA has immunostimulatory f...

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Detalhes bibliográficos
Main Authors: Sjölinder, Mikael, Altenbacher, Georg, Wang, Xiao, Gao, Yumin, Hansson, Charlotta, Sjölinder, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486040/
https://ncbi.nlm.nih.gov/pubmed/22949555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00456-12
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