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Important Role for Toll-Like Receptor 9 in Host Defense against Meningococcal Sepsis

Neisseria meningitidis is a leading cause of meningitis and sepsis. The pathogenesis of meningococcal disease is determined by both bacterial virulence factors and the host inflammatory response. Toll-like receptors (TLRs) are prominent activators of the inflammatory response, and TLR2, -4, and -9 h...

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Autors principals: Sjölinder, Hong, Mogensen, Trine H., Kilian, Mogens, Jonsson, Ann-Beth, Paludan, Søren R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573357/
https://ncbi.nlm.nih.gov/pubmed/18794294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00615-08
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