A Recombinant Clumping Factor A-Containing Vaccine Induces Functional Antibodies to Staphylococcus aureus That Are Not Observed after Natural Exposure

Staphylococcus aureus is a Gram-positive pathogen that causes devastating disease and whose pathogenesis is dependent on interactions with host cell factors. Staphylococcal clumping factor A (ClfA) is a highly conserved fibrinogen (Fg)-binding protein and virulence factor that contributes to host ti...

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Detalhes bibliográficos
Main Authors: Hawkins, Julio, Kodali, Srinivas, Matsuka, Yury V., McNeil, Lisa K., Mininni, Terri, Scully, Ingrid L., Vernachio, John H., Severina, Elena, Girgenti, Douglas, Jansen, Kathrin U., Anderson, Annaliesa S., Donald, Robert G. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485874/
https://ncbi.nlm.nih.gov/pubmed/22896688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00354-12
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