High Resolution Mapping of Bactericidal Monoclonal Antibody Binding Epitopes on Staphylococcus aureus Antigen MntC

The Staphylococcus aureus manganese transporter protein MntC is under investigation as a component of a prophylactic S.aureus vaccine. Passive immunization with monoclonal antibodies mAB 305-78-7 and mAB 305-101-8 produced using MntC was shown to significantly reduce S. aureus burden in an infant ra...

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Foilsithe in:PLoS Pathog
Main Authors: Gribenko, Alexey V., Parris, Kevin, Mosyak, Lidia, Li, Sheng, Handke, Luke, Hawkins, Julio C., Severina, Elena, Matsuka, Yury V., Anderson, Annaliesa S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045189/
https://ncbi.nlm.nih.gov/pubmed/27689696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005908
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