Piperonylic Acid, a Selective, Mechanism-Based Inactivator of the trans-Cinnamate 4-Hydroxylase: A New Tool to Control the Flux of Metabolites in the Phenylpropanoid Pathway

Piperonylic acid (PA) is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. The CYP73A subfamily of plant P450s catalyzes trans-cinnamic acid 4-hydroxylation, the second step of the general phenylpropanoid pathway. We show that when incubat...

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Publicado en:	Plant Physiol
Autores principales:	Schalk, Michel, Cabello-Hurtado, Francisco, Pierrel, Marie-Agnès, Atanossova, Rossitza, Saindrenan, Patrick, Werck-Reichhart, Danièle
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 1998
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34858/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733540/ https://ncbi.nlm.nih.govhttps://doi.org/10.1104/pp.118.1.209
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