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Piperonylic Acid, a Selective, Mechanism-Based Inactivator of the trans-Cinnamate 4-Hydroxylase: A New Tool to Control the Flux of Metabolites in the Phenylpropanoid Pathway

Piperonylic acid (PA) is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. The CYP73A subfamily of plant P450s catalyzes trans-cinnamic acid 4-hydroxylation, the second step of the general phenylpropanoid pathway. We show that when incubat...

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Detalhes bibliográficos
Main Authors: Schalk, Michel, Cabello-Hurtado, Francisco, Pierrel, Marie-Agnès, Atanossova, Rossitza, Saindrenan, Patrick, Werck-Reichhart, Danièle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Plant Physiologists 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34858/
https://ncbi.nlm.nih.gov/pubmed/9733540
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