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Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2.

Carbocyclic thromboxane A2 [2 beta (Z),3 alpha- (1E,3R*)-3-(3-hydroxy(1-octenyl)-bicyclo[3.1.1]hept-2-yl-5-heptenoic acid], a stable analog of thromboxane A2, has been tested for its physiologic properties. Carbocyclic thromboxane A2 is a potent coronary vasoconstrictor, stimulating cornonary vascul...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lefer, A M, Smith, E F, Araki, H, Smith, J B, Aharony, D, Claremon, D A, Magolda, R L, Nicolaou, K C
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1980
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348566/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6929517/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.3.1706
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