Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2.

Carbocyclic thromboxane A2 [2 beta (Z),3 alpha- (1E,3R*)-3-(3-hydroxy(1-octenyl)-bicyclo[3.1.1]hept-2-yl-5-heptenoic acid], a stable analog of thromboxane A2, has been tested for its physiologic properties. Carbocyclic thromboxane A2 is a potent coronary vasoconstrictor, stimulating cornonary vascul...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Lefer, A M, Smith, E F, Araki, H, Smith, J B, Aharony, D, Claremon, D A, Magolda, R L, Nicolaou, K C
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1980
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348566/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6929517/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.3.1706
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