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Benzodiazepine receptor protein identified and visualized in brain tissue by a photoaffinity label.
Flunitrazepam, a potent benzodiazepine, reversibly binds to the benzodiazepine receptor with high affinity. When irradiated with UV light, flunitrazepam was irreversibly linked to brain tissue. Incorporation of [3H]flunitrazepam was inhibited by other benzodiazepines with a potency corresponding to...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1980
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348558/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6103538/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.3.1666 |
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