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Protein Clearance Mechanisms of Alpha-Synuclein and Amyloid-Beta in Lewy Body Disorders

Protein clearance is critical for the maintenance of the integrity of neuronal cells, and there is accumulating evidence that in most—if not all—neurodegenerative disorders, impaired protein clearance fundamentally contributes to functional and structural alterations eventually leading to clinical s...

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Hlavní autoři: Deleidi, Michela, Maetzler, Walter
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485523/
https://ncbi.nlm.nih.gov/pubmed/23133788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/391438
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