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Clonal anergy: Persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen

The purpose of these experiments was to determine the degree of reduction in the number of antigen-binding B lymphocytes in the spleens of mice that had been rendered tolerant in the perinatal period. Newborn or pregnant mice were injected with fluorescein (Flu) coupled onto human gamma globulin, an...

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Publicado en:Proc Natl Acad Sci U S A
Principais autores: Nossal, G. J. V., Pike, Beverley L.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1980
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6966401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.3.1602
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