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Clonal anergy: Persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen

The purpose of these experiments was to determine the degree of reduction in the number of antigen-binding B lymphocytes in the spleens of mice that had been rendered tolerant in the perinatal period. Newborn or pregnant mice were injected with fluorescein (Flu) coupled onto human gamma globulin, an...

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Detalhes bibliográficos
Main Authors: Nossal, G. J. V., Pike, Beverley L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC348545/
https://ncbi.nlm.nih.gov/pubmed/6966401
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