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Curcumin induces human cathelicidin antimicrobial peptide gene expression through a vitamin D receptor-independent pathway

The vitamin D receptor (VDR) mediates the pleiotropic biologic effects of 1α,25 dihydroxy-vitamin D(3). Recent in vitro studies suggested that curcumin and poly-unsaturated fatty acids (PUFAs) also bind to VDR with low affinity. As potential ligands for the VDR, we hypothesized that curcumin and PUF...

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Bibliografski detalji
Glavni autori: Guo, Chunxiao, Rosoha, Elena, Lowry, Malcolm B., Borregaard, Niels, Gombart, Adrian F.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485441/
https://ncbi.nlm.nih.gov/pubmed/22841393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2012.04.002
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