A mouse model for vitamin D-induced human cathelicidin antimicrobial peptide gene expression

In humans and other primates, 1,25(OH)(2)vitamin D3 regulates the expression of the cathelicidin antimicrobial peptide (CAMP) gene via toll-like receptor (TLR) signaling that activates the vitamin D pathway. Mice and other mammals lack the vitamin D response element (VDRE) in their CAMP promoters. T...

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Publicat a:J Steroid Biochem Mol Biol
Autors principals: Lowry, Malcolm B., Guo, Chunxiao, Zhang, Yang, Fantacone, Mary L., Logan, Isabelle E., Campbell, Yan, Zhang, Weijian, Le, Mai, Indra, Arup K., Ganguli-Indra, Gitali, Xie, Jingwei, Gallo, Richard L., Koeffler, H. Phillip, Gombart, Adrian F.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089838/
https://ncbi.nlm.nih.gov/pubmed/31783153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2019.105552
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