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Palladium-Catalyzed N-Monoarylation of Amidines and a One-Pot Synthesis of Quinazoline Derivatives

[Image: see text] A method for the Pd-catalyzed N-arylation of both aryl and alkyl amidines with a wide range of aryl bromides, chlorides, and triflates is described. The reactions proceed in short reaction times and with excellent selectivity for monoarylation. A one-pot synthesis of quinazoline de...

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Detalhes bibliográficos
Main Authors: McGowan, Meredeth A., McAvoy, Camille Z., Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485433/
https://ncbi.nlm.nih.gov/pubmed/22765354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301700y
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