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Palladium-Catalyzed N-Arylation of 2-Aminothiazoles

[Image: see text] A method for the Pd-catalyzed coupling of 2-aminothiazole derivatives with aryl bromides and triflates is described. Significantly, for this class of nucleophiles, the coupling exhibits a broad substrate scope and proceeds with a reasonable catalyst loading. Furthermore, an interes...

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Autors principals: McGowan, Meredeth A., Henderson, Jaclyn L., Buchwald, Stephen L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319723/
https://ncbi.nlm.nih.gov/pubmed/22394197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300178j
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