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Variants Identified in a GWAS Meta-Analysis for Blood Lipids Are Associated with the Lipid Response to Fenofibrate

A recent large-scale meta-analysis of genome-wide studies has identified 95 loci, 59 of them novel, as statistically significant predictors of blood lipid traits; we tested whether the same loci explain the observed heterogeneity in response to lipid-lowering therapy with fenofibrate. Using data fro...

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Autors principals: Aslibekyan, Stella, Goodarzi, Mark O., Frazier-Wood, Alexis C., Yan, Xiaofei, Irvin, Marguerite R., Kim, Eric, Tiwari, Hemant K., Guo, Xiuqing, Straka, Robert J., Taylor, Kent D., Tsai, Michael Y., Hopkins, Paul N., Korenman, Stanley G., Borecki, Ingrid B., Chen, Yii-Der I., Ordovas, Jose M., Rotter, Jerome I., Arnett, Donna K.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485381/
https://ncbi.nlm.nih.gov/pubmed/23119086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048663
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