Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate

OBJECTIVE: A shift towards overall larger very low-density lipoprotein (VLDL), and smaller low-density lipoprotein and high-density lipoprotein (HDL) diameters occurs in insulin resistance (IR), which reflects shifts in the distribution of the subfraction concentrations. Fenofibrate, indicated for h...

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Autori principali: Frazier-Wood, Alexis C., Aslibekyan, Stella, Borecki, Ingrid B., Hopkins, Paul N., Lai, Chao-Qiang, Ordovas, Jose M., Straka, Robert J., Tiwari, Hemant K., Arnett, Donna K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760420/
https://ncbi.nlm.nih.gov/pubmed/22890011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328357f6af
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