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Fasudil Protects the Heart against Ischemia-Reperfusion Injury by Attenuating Endoplasmic Reticulum Stress and Modulating SERCA Activity: The Differential Role for PI3K/Akt and JAK2/STAT3 Signaling Pathways

Disordered calcium homeostasis can lead to endoplasmic reticulum (ER) stress. Our previous data showed that time course activation of ER stress contributes to time-related increase in ischemia-reperfusion (I/R) injury. However, it has not been tested whether PI3K/Akt and JAK2/STAT3 pathways play dif...

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Detalhes bibliográficos
Main Authors: Li, Yapeng, Zhu, Wei, Tao, Jianping, Xin, Ping, Liu, Mingya, Li, Jingbo, Wei, Meng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485283/
https://ncbi.nlm.nih.gov/pubmed/23118936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048115
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