Role of the degradation process in the mitogenic effect of epidermal growth factor
The protease inhibitor leupeptin inhibits the degradation process of (125)I-labeled epidermal growth factor ((125)I-EGF) by cultured bovine granulosa cells. At 80 μg/ml, leupeptin inhibited the appearance of degradation products of (125)I-EGF in the medium by 95% during 1 hr of incubation and by 90%...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1980
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348516/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6966398/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.3.1466 |
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