Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP Kinase-dependent and -independent mechanisms in mouse RAW264.7 macrophages

BACKGROUND: Carbon nanotubes (CNTs) are engineered graphene cylinders with numerous applications in engineering, electronics and medicine. However, CNTs cause inflammation and fibrosis in the rodent lung, suggesting a potential human health risk. We hypothesized that multi-walled CNTs (MWCNTs) induc...

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Detalhes bibliográficos
Main Authors: Lee, Jong Kwon, Sayers, Brian C, Chun, Kyung-Soo, Lao, Huei-Chen, Shipley-Phillips, Jeanette K, Bonner, James C, Langenbach, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485091/
https://ncbi.nlm.nih.gov/pubmed/22571318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-9-14
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