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Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis

Fibrodysplasia ossificans progressiva (FOP; MIM #135100) is a debilitating genetic disorder of connective tissue metamorphosis. It is characterized by malformation of the great (big) toes during embryonic skeletal development and by progressive heterotopic endochondral ossification (HEO) postnatally...

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Bibliographic Details
Main Authors: Kaplan, Frederick S., Chakkalakal, Salin A., Shore, Eileen M.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Limited 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484858/
https://ncbi.nlm.nih.gov/pubmed/23115204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010280
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