Parallel assessment of CpG methylation by two-color hybridization with oligonucleotide arrays

We have developed a method for the parallel analysis of multiple CpG sites in genomic DNA for their state of methylation. Hypermethylation of CpG islands within the promoters and 5′ exons of genes has been found to be a mechanism of transcriptional inactivation associated with a variety of tumors. T...

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Autors principals: Balog, Robert P., de Souza, Y. Emi Ponce, Tang, Hue M., DeMasellis, Gina M., Gao, Boning, Avila, Adrian, Gaban, Desmond J., Mittelman, David, Minna, John D., Luebke, Kevin J., Garner, Harold R.
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484840/
https://ncbi.nlm.nih.gov/pubmed/12413464
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