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Site-specific phosphorylation of the α subunit of eukaryotic initiation factor eIF-2 by the heme-regulated and double-stranded RNA-activated eIF-2α kinases from rabbit reticulocyte lysates

The site specificity of phosphorylation of the α subunit of eukaryotic initiation factor 2 (eIF-2α) by the heme-regulated and double-stranded RNA-activated eIF-2α kinases were compared by phosphopeptide mapping. eIF-2α was maximally phosphorylated in vitro with [γ-(32)P]ATP and either crude or parti...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ernst, Vivian, Levin, Daniel H., Leroux, Alena, London, Irving M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1980
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Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348479/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6929486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.3.1286
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