Nonreproducibility of “Snap-Frozen” Rectal Biopsies for Later Use in Ex Vivo Explant Infectibility Studies

Sexual transmission accounts for the majority of new HIV infections worldwide with sexually exposed cervicovaginal and colorectal mucosae being primary sites of infection. Two recent Phase 1 rectal microbicide trials included, as an ancillary endpoint, suppression of ex vivo HIV infection of in vivo...

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Bibliografiske detaljer
Main Authors: McGowan, Ian, Tanner, Karen, Elliott, Julie, Ibarrondo, Javier, Khanukhova, Elena, McDonald, Charina, Saunders, Terry, Zhou, Ying, Anton, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2012
Fag:
Preclinical Studies/Drug Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484788/
https://ncbi.nlm.nih.gov/pubmed/22831398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0062
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