Nonreproducibility of “Snap-Frozen” Rectal Biopsies for Later Use in Ex Vivo Explant Infectibility Studies

Sexual transmission accounts for the majority of new HIV infections worldwide with sexually exposed cervicovaginal and colorectal mucosae being primary sites of infection. Two recent Phase 1 rectal microbicide trials included, as an ancillary endpoint, suppression of ex vivo HIV infection of in vivo...

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Bibliografiska uppgifter
Huvudupphovsmän: McGowan, Ian, Tanner, Karen, Elliott, Julie, Ibarrondo, Javier, Khanukhova, Elena, McDonald, Charina, Saunders, Terry, Zhou, Ying, Anton, Peter A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2012
Ämnen:
Preclinical Studies/Drug Development
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484788/
https://ncbi.nlm.nih.gov/pubmed/22831398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0062
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