Mitochondrial Dynamics Regulate Growth Cone Motility, Guidance, and Neurite Growth Rate in Perinatal Retinal Ganglion Cells In Vitro

PURPOSE. Retinal ganglion cell (RGC) death and failed axonal regeneration after trauma or disease, including glaucomatous and mitochondrial optic neuropathies, are linked increasingly to dysfunctional mitochondrial dynamics. However, how mitochondrial dynamics influence axon growth largely is unstud...

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Autori principali: Steketee, Michael B., Moysidis, Stavros N., Weinstein, Jessica E., Kreymerman, Alex, Silva, Jose P., Iqbal, Siraj, Goldberg, Jeffrey L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484733/
https://ncbi.nlm.nih.gov/pubmed/23049086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10298
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