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A Forward Genetic Screen Identifies Eukaryotic Translation Initiation Factor 3, Subunit H (eIF3h), as an Enhancer of Variegation in the Mouse

We have used a forward genetic screen to identify genes required for transgene silencing in the mouse. Previously these genes were found using candidate-based sequencing, a slow and labor-intensive process. Recently, whole-exome deep sequencing has accelerated our ability to find the causative point...

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מידע ביבליוגרפי
Main Authors: Daxinger, Lucia, Oey, Harald, Apedaile, Anwyn, Sutton, Joanne, Ashe, Alyson, Whitelaw, Emma
פורמט: Artigo
שפה:Inglês
יצא לאור: Genetics Society of America 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484669/
https://ncbi.nlm.nih.gov/pubmed/23173090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.004036
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