Nanog signaling in cancer promotes stem-like phenotype and immune evasion

Adaptation of tumor cells to the host is a major cause of cancer progression, failure of therapy, and ultimately death. Immune selection drives this adaptation in human cancer by enriching tumor cells with a cancer stem cell–like (CSC-like) phenotype that makes them resistant to CTL-mediated apoptos...

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Hlavní autoři: Noh, Kyung Hee, Kim, Bo Wook, Song, Kwon-Ho, Cho, Hanbyoul, Lee, Young-Ho, Kim, Jin Hee, Chung, Joon-Yong, Kim, Jae-Hoon, Hewitt, Stephen M., Seong, Seung-Yong, Mao, Chih-Ping, Wu, T.-C., Kim, Tae Woo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484451/
https://ncbi.nlm.nih.gov/pubmed/23093782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64057
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