Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans

Pancreatic ductal adenocarcinoma is an aggressive cancer that interacts with stromal cells to produce a highly inflammatory tumor microenvironment that promotes tumor growth and invasiveness. The precise interplay between tumor and stroma remains poorly understood. TLRs mediate interactions between...

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Hauptverfasser: Ochi, Atsuo, Graffeo, Christopher S., Zambirinis, Constantinos P., Rehman, Adeel, Hackman, Michael, Fallon, Nina, Barilla, Rocky M., Henning, Justin R., Jamal, Mohsin, Rao, Raghavendra, Greco, Stephanie, Deutsch, Michael, Medina-Zea, Marco V., Saeed, Usama Bin, Ego-Osuala, Melvin O., Hajdu, Cristina, Miller, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484447/
https://ncbi.nlm.nih.gov/pubmed/23023703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63606
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