Hypoxic pulmonary vasoconstriction requires connexin 40–mediated endothelial signal conduction

Hypoxic pulmonary vasoconstriction (HPV) is a physiological mechanism by which pulmonary arteries constrict in hypoxic lung areas in order to redirect blood flow to areas with greater oxygen supply. Both oxygen sensing and the contractile response are thought to be intrinsic to pulmonary arterial sm...

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Autores principales: Wang, Liming, Yin, Jun, Nickles, Hannah T., Ranke, Hannes, Tabuchi, Arata, Hoffmann, Julia, Tabeling, Christoph, Barbosa-Sicard, Eduardo, Chanson, Marc, Kwak, Brenda R., Shin, Hee-Sup, Wu, Songwei, Isakson, Brant E., Witzenrath, Martin, de Wit, Cor, Fleming, Ingrid, Kuppe, Hermann, Kuebler, Wolfgang M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484430/
https://ncbi.nlm.nih.gov/pubmed/23093775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59176
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